Researchers Treat Depression by Reversing Brain Signals Traveling the Wrong Way

Transcranial magnetic stimulation (TMS), a treatment used to alleviate severe depression, has been found to work by reversing abnormal brain signals, according to research led by Stanford Medicine scientists. The study revealed that TMS modifies the flow of neural activity in the brain, with depressed patients often exhibiting a reversal of the normal flow between key brain regions. The researchers also discovered that the direction of brain activity could serve as a biomarker for diagnosing depression. If the initial findings are replicated in larger studies, it could pave the way for personalized targeting of depression treatment based on this biomarker.

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